abstract：BACKGROUND AND AIMS:Risk factors for osteoporotic fracture as well as inpatient utilization and mortality have not been thoroughly studied in patients with cirrhosis. We analyzed data from a national database to determine fracture risk in patients with cirrhosis, specific risk factors, and the effect of fractures on he...

journal_title：Journal of clinical gastroenterology

authors： Patel A,Silverman S,Baghdadi J,Shah O,Sundaram V

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Diverticular disease (DD) is a common gastrointestinal inflammatory disorder associated with an enteric neuropathy. Although enteric glial cells (EGCs) are essential regulators of intestinal inflammation and motility functions, their contribution to the pathophysiology of DD remains unclear. Therefore, we an...

journal_title：Journal of clinical gastroenterology

authors： Cossais F,Leuschner S,Barrenschee M,Lange C,Ebsen M,Vogel I,Böttner M,Wedel T

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:The cause of abdominal pain (AP) in gastroparesis (Gp) is often not known; hence, its treatment can be challenging. Preoccupation with or increased attention (hypervigilance) to pain is associated with perceived pain severity and psychosocial disability. The aims of this study were to (1) characterize AP i...

journal_title：Journal of clinical gastroenterology

authors： Jehangir A,Abdallah RT,Parkman HP

更新日期：2019-07-01 00:00:00

abstract：:Portal hypertension, a consequence of end-stage liver disease and liver cirrhosis can lead to significant morbidity and mortality for patients through abnormal fluid accumulation as well as the formation of portosystemic shunts and varices. Treatment of the sequelae of portal hypertension can be achieved through endov...

journal_title：Journal of clinical gastroenterology

authors： Shreve L,Lee EW

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The standard of care for managing pancreaticobiliary disease in altered Roux-en-Y gastric bypass patients is laparoscopy-assisted endoscopic retrograde cholangiopancreatography (LA-ERCP), but is limited by cost and adverse events. Recently a minimally invasive, completely endoscopic approach using e...

journal_title：Journal of clinical gastroenterology

authors： Kedia P,Tarnasky PR,Nieto J,Steele SL,Siddiqui A,Xu MM,Tyberg A,Gaidhane M,Kahaleh M

更新日期：2019-04-01 00:00:00

abstract：GOALS:To assess the effect of unilateral versus bilateral lung transplantation (LTx) on esophageal motility and gastroesophageal reflux, and the association with the development of obstructive chronic lung allograft dysfunction (o-CLAD). BACKGROUND:We have shown that esophagogastric junction outflow obstruction, incom...

journal_title：Journal of clinical gastroenterology

authors： Tangaroonsanti A,Lee AS,Vela MF,Crowell MD,Erasmus D,Keller C,Mallea J,Alvarez F,Almansa C,DeVault KR,Houghton LA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND STUDY AIM:Newer capsule with a panoramic viewing mode is available and might increase the detection rate of bleeding lesions in patients with obscure gastrointestinal bleeding (OGIB). Furthermore, an improved patient acceptance rate is expected. MATERIALS AND METHODS:In a randomized prospective comparat...

journal_title：Journal of clinical gastroenterology

authors： Zwinger LL,Siegmund B,Stroux A,Adler A,Veltzke-Schlieker W,Wentrup R,Jürgensen C,Wiedenmann B,Wiedbrauck F,Hollerbach S,Liceni T,Bojarski C

更新日期：2019-03-01 00:00:00

abstract：GOAL:The goal of this study is to determine factors associated with performance of duodenal biopsy during upper endoscopy. BACKGROUND:Celiac disease (CD) prevalence approaches 1% in the United States and Europe, yet CD remains underdiagnosed, in part because of low rates of duodenal biopsy during upper endoscopy. We a...

journal_title：Journal of clinical gastroenterology

authors： Pitman M,Sanders DS,Green PHR,Lebwohl B

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Gastroparesis, a chronic gastrointestinal disorder defined by delayed stomach emptying in the absence of obstruction, is often associated with frequent and costly visits to the emergency department (ED). The aim of this study was to analyze trends in gastroparesis-related ED visits from 2006 to 2013...

journal_title：Journal of clinical gastroenterology

authors： Hirsch W,Nee J,Ballou S,Petersen T,Friedlander D,Lee HN,Cheng V,Lembo A

更新日期：2019-02-01 00:00:00

abstract：:Etiology of inflammatory bowel disease (IBD) is not yet completely understood, but it is hypothesized that a disruption of the immune tolerance to gut microbiota, due to several potential factors like an abnormal gut microbiota composition and activity, may lead to IBD occurrence. Manipulation of the intestinal microb...

journal_title：Journal of clinical gastroenterology

authors： Scarpato E,Russo M,Staiano A

更新日期：2018-11-01 00:00:00

abstract：:Probiotics are investigated as single-strain and multistrain products. In the market, however, there is an increasing tendency to work with multistrain probiotics, in particular, products with a high number of different strains. There are some thoughts behind this: more strains imply more chances of success; it can me...

journal_title：Journal of clinical gastroenterology

authors： Ouwehand AC,Invernici MM,Furlaneto FAC,Messora MR

更新日期：2018-11-01 00:00:00

abstract：:The methods used to discern the structure (anatomy) and function (physiology) of the indigenous microbiota can be divided according to which aspect of the microbiota they can interrogate and are positioned accordingly. At the most basic level, methods can simply describe the community structure of the microbiota, that...

journal_title：Journal of clinical gastroenterology

authors： Koch M

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Gastrointestinal angiodysplasias (GIAD) are commonly diagnosed in the small bowel but can be located in other areas of the gastrointestinal tract. About half of patients diagnosed with GIAD have more than 1 lesion and 20% of patients have GIAD in both the small bowel and a source outside of the small bowel (...

journal_title：Journal of clinical gastroenterology

authors： Mai SH,Chao DC,Liao SY,Jackson CS

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Clostridium difficile is a bacterial pathogen associated with significant morbidity and mortality in patients with cirrhosis. GOALS:Our primary aim is to identify variables that are predictive of poor outcomes in cirrhosis patients with C. difficile infection (CDI). We also aim to further characterize the r...

journal_title：Journal of clinical gastroenterology

authors： Smith EZ,Northup PG,Argo CK

更新日期：2018-09-01 00:00:00

abstract：GOALS:In order to provide a comparative evaluation of available pharmacologic treatments for eosinophilic esophagitis (EoE), we conducted a network meta-analysis. BACKGROUND:A variety of pharmacologic treatments for EoE have been reported, however there exists a paucity of direct comparisons. STUDY:We searched random...

journal_title：Journal of clinical gastroenterology

authors： Tomizawa Y,Melek J,Komaki Y,Kavitt RT,Sakuraba A

更新日期：2018-08-01 00:00:00

abstract：:New-onset diabetes mellitus (DM) is one of the first symptoms of pancreatic adenocarcinoma (PDAC). The frequency of endocrine disorders is estimated between 40% and 80% in patients with pancreatic cancer. DM is a risk factor for cancer development but it may also be a consequence of the tumor growth. Data confirming t...

journal_title：Journal of clinical gastroenterology

authors： Wlodarczyk B,Gasiorowska A,Malecka-Panas E

更新日期：2018-08-01 00:00:00

abstract：GOALS:The aim of this study was to assess whether sustained 6-thioguaninenucleotide (6-TGN) levels were associated with improved long-term outcomes in patients with inflammatory bowel diseases (IBD). BACKGROUND:Cross-sectional data have shown that thiopurine metabolites are correlated with clinical efficacy in patient...

journal_title：Journal of clinical gastroenterology

authors： Yarur AJ,Gondal B,Hirsch A,Christensen B,Cohen RD,Rubin DT

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Fatigue is common in inflammatory bowel disease (IBD) patients and is associated with factors such as psychopathology, sleep quality, and disease activity. GOAL:To investigate the combined role of all the above factors in the burden of fatigue among IBD patients. STUDY:We conducted an observational study o...

journal_title：Journal of clinical gastroenterology

authors： Hashash JG,Ramos-Rivers C,Youk A,Chiu WK,Duff K,Regueiro M,Binion DG,Koutroubakis I,Vachon A,Benhayon D,Dunn MA,Szigethy EM

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Split-dose regimens (SpDs) were recommended as a first choice for bowel preparation, whereas same-day regimens (SaDs) were recommended as an alternative; however, randomized trials compared them with mixed results. The meta-analysis was aimed at clarifying efficacy level between the 2 regimens. MATERIALS AN...

journal_title：Journal of clinical gastroenterology

authors： Cheng YL,Huang KW,Liao WC,Luo JC,Lan KH,Su CW,Wang YJ,Hou MC

更新日期：2018-05-01 00:00:00

abstract：:Endoscopy imaging of the gastrointestinal (GI) tract has evolved tremendously over the last few decades. Key milestones in the development of endoscopy imaging include the use of various dyes for chromoendoscopy, the application of optical magnification in endoscopy, the introduction of high-definition image capturing...

journal_title：Journal of clinical gastroenterology

authors： Ho SH,Uedo N,Aso A,Shimizu S,Saito Y,Yao K,Goh KL

更新日期：2018-04-01 00:00:00

abstract：GOAL:To provide the statistical predictive model for neoplastic potential of gallbladder polyp (GBP). BACKGROUND:Many studies have attempted to define the risk factors for neoplastic potential of GBP. It remains difficult to precisely adapt the reported risk factors for the decision of surgery. Estimating the probabil...

journal_title：Journal of clinical gastroenterology

authors： Yang JI,Lee JK,Ahn DG,Park JK,Lee KH,Lee KT,Chi SA,Jung SH

更新日期：2018-03-01 00:00:00

abstract：GOAL:To determine the effect of the specific carbohydrate diet (SCD) on active inflammatory bowel disease (IBD). BACKGROUND:IBD is a chronic idiopathic inflammatory intestinal disorder associated with fecal dysbiosis. Diet is a potential therapeutic option for IBD based on the hypothesis that changing the fecal dysbio...

journal_title：Journal of clinical gastroenterology

authors： Suskind DL,Cohen SA,Brittnacher MJ,Wahbeh G,Lee D,Shaffer ML,Braly K,Hayden HS,Klein J,Gold B,Giefer M,Stallworth A,Miller SI

更新日期：2018-02-01 00:00:00

abstract：GOAL:The purpose of this study was to characterize outcomes of esophagorespiratory fistulas (ERF) by etiology and initial treatment strategy. BACKGROUND:ERF is a morbid condition for which optimal treatment strategies and outcomes are still in evolution. STUDY:Medical records and images were reviewed for all patients...

journal_title：Journal of clinical gastroenterology

authors： Lenz CJ,Bick BL,Katzka D,Nichols FC,Depew ZS,Wong Kee Song LM,Baron TH,Buttar NS,Maldonado F,Enders FT,Harmsen WS,Dierkhising RA,Topazian MD

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND AIM:Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of cancer; most patients die during the first 6 months after diagnosis. With a 5% 5-year survival rate, is the fourth leading cause of cancer death in developed countries. In this regard, several clinical, histopathologic and bio...

journal_title：Journal of clinical gastroenterology

authors： Macías N,Sayagués JM,Esteban C,Iglesias M,González LM,Quiñones-Sampedro J,Gutiérrez ML,Corchete LA,Abad MM,Bengoechea O,Muñoz-Bellvis L

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND THE STUDY AIM:Crohn's disease (CD) is a chronic inflammatory disorder defined as a transmural inflammation of the bowel wall, affecting the small and large intestine. The Capsule Endoscopy Crohn's Disease Activity Index (CECDAI or Niv score) was devised to measure mucosal disease activity. We extended th...

journal_title：Journal of clinical gastroenterology

authors： Niv Y,Gal E,Gabovitz V,Hershkovitz M,Lichtenstein L,Avni I

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Although the diagnostic process in celiac disease (CeD) has been addressed in several international guidelines, little is known about the actual proceeding in current clinical practice. This study investigated the initial presentation, the diagnostic process, follow-up evaluations, and adherence to a gluten-...

journal_title：Journal of clinical gastroenterology

authors： Vavricka SR,Stelzer T,Lattmann J,Stotz M,Lehmann R,Zeitz J,Scharl M,Misselwitz B,Pohl D,Fried M,Tutuian R,Fasano A,Schoepfer AM,Rogler G,Biedermann L,Greuter T

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Vitamin deficiency is frequently associated with inflammatory bowel disease (IBD). Supplementation of vitamins could thus serve as an adjunctive therapy. The present meta-analysis reviews the deficiencies and alterations in serum fat-soluble vitamins (A, D, E, and K) reported in IBD patients. MATERIALS AND ...

journal_title：Journal of clinical gastroenterology

authors： Fabisiak N,Fabisiak A,Watala C,Fichna J

更新日期：2017-11-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection due to mother-to-child transmission during the perinatal period remains an important global health problem. Despite standard passive-active immunoprophylaxis with hepatitis B immunoglobulin and hepatitis B vaccine in neonates, up to 8.5% of newborns still acquire HBV infection...

journal_title：Journal of clinical gastroenterology

authors： Li J,Chang MS,Tran TT,Nguyen MH

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Groove pancreatitis (GP) is a focal form of chronic pancreatitis affecting the paraduodenal groove area, for which consensus on diagnosis and management is lacking. GOALS:We performed a systematic review of the literature to determine patient characteristics and imaging features of GP and to evaluate clinic...

journal_title：Journal of clinical gastroenterology

authors： Kager LM,Lekkerkerker SJ,Arvanitakis M,Delhaye M,Fockens P,Boermeester MA,van Hooft JE,Besselink MG

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Hypertriglyceridemia has been positively associated with the risk of acute pancreatitis (AP), but whether increased triglyceride (TG) levels are associated with the severity of AP remains unknown. To this, a meta-analysis was conducted to assess the effect of elevated serum TG on the prognosis of AP. METHOD...

journal_title：Journal of clinical gastroenterology

authors： Wang Q,Wang G,Qiu Z,He X,Liu C

更新日期：2017-08-01 00:00:00

abstract：:Colorectal cancer (CRC), gastroesophageal reflux disease (GERD), inflammatory bowel disease (IBD), and nonalcoholic fatty liver disease are considered important emerging diseases in the Asia Pacific (AP) region. The incidence rate of CRC is the highest among gastrointestinal cancers in the region surpassing that of ga...

journal_title：Journal of clinical gastroenterology

authors： Goh KL

更新日期：2017-07-01 00:00:00

abstract：GOALS:To determine the proportion of patients with gastroesophageal reflux disease who are on proton pump inhibitors (PPIs) who could reduce their prior dosage by half, and identify predictors of successful step-down. BACKGROUND:Appropriate hypergastrinemia results from gastric acid inhibition. A gender difference in ...

journal_title：Journal of clinical gastroenterology

authors： Helgadóttir H,Metz DC,Lund SH,Gizurarson S,Jacobsen EI,Asgeirsdóttir GA,Yngadóttir Y,Björnsson ES

更新日期：2017-07-01 00:00:00

abstract：GOALS:We intended to identify the factors associated with missed appointments at a gastroenterology (GI) clinic in an academic setting. BACKGROUND:Missed clinic appointments reduce clinic efficiency, waste resources, and increase costs. Limited data exist on subspecialty clinic attendance. STUDY:We performed a case-c...

journal_title：Journal of clinical gastroenterology

authors： Shrestha MP,Hu C,Taleban S

更新日期：2017-05-01 00:00:00

abstract：GOALS:Our aim was to study the prevalence of dysplasia and progression to high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) in African Americans (AA) with Barrett's esophagus (BE) and compare it with that of non-Hispanic white (NHW) controls. BACKGROUND:BE, a precursor of EAC, is a disease of predominantl...

journal_title：Journal of clinical gastroenterology

authors： Thota PN,Zackria S,Sanaka MR,Patil D,Goldblum J,Lopez R,Chak A

更新日期：2017-05-01 00:00:00

abstract：:Fecal incontinence (FI), defined as the involuntary loss of solid or liquid feces through the anus is a prevalent condition with significant effects on quality of life. FI can affect individuals of all ages and in many cases greatly impairs quality of life but, incontinent patients should not accept their debility as ...

journal_title：Journal of clinical gastroenterology

authors： Guillaume A,Salem AE,Garcia P,Chander Roland B

更新日期：2017-04-01 00:00:00

abstract：GOALS:To evaluate age-specific disparities in cancer stage at diagnosis, receipt of treatment, and survival among adults with hepatocellular carcinoma (HCC). BACKGROUND:HCC has become the fastest rising cause of cancer-related deaths in the United States. The aging population coupled with the rising incidence of HCC w...

journal_title：Journal of clinical gastroenterology

authors： Yan M,Ha J,Aguilar M,Liu B,Frenette CT,Bhuket T,Wong RJ

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND/AIMS:Split-dose polyethylene glycol (PEG) is considered a standard bowel preparation regimen for colonoscopy in the general population. However, it is not clear whether the regimen is optimal for colonoscopy in diabetic patients. The aim of this study was to compare the efficacy and tolerability of split-dos...

journal_title：Journal of clinical gastroenterology

authors： Kim YH,Seo EH,Lee JS,Lee SH,Park HS,Choi SH,Park JY,Lee CW

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:For patients with Crohn's disease (CD) who have colonoscopy during periods of clinical remission, the utility of taking ileocolonic biopsy specimens to assess disease activity is disputed. GOALS:We explored the clinical implications of histologic disease activity in such patients. STUDY:We reviewed medical...

journal_title：Journal of clinical gastroenterology

authors： Brennan GT,Melton SD,Spechler SJ,Feagins LA

更新日期：2017-01-01 00:00:00

abstract：GOALS:To report the clinical profile and natural course in a large series of patients with hypertriglyceridemia (HTG) and acute pancreatitis (AP). BACKGROUND:The natural history of HTG-related pancreatitis is poorly defined. STUDY:Medical records of 121 patients with serum triglycerides (TG) levels of ≥500 mg/dL suff...

journal_title：Journal of clinical gastroenterology

authors： Vipperla K,Somerville C,Furlan A,Koutroumpakis E,Saul M,Chennat J,Rabinovitz M,Whitcomb DC,Slivka A,Papachristou GI,Yadav D

更新日期：2017-01-01 00:00:00

abstract：:Pancreatic fluid collections (PFCs) may develop due to inflammation secondary to acute and/or chronic pancreatitis, trauma, surgery, or obstruction from solid or cystic neoplasms. PFCs can be drained percutaneously, surgically, or endoscopically with endoscopic ultrasound-guided cyst gastrostomy and/or transpapillary ...

journal_title：Journal of clinical gastroenterology

authors： Muniraj T,Jamidar PA,Nealon WH,Aslanian HR

更新日期：2017-01-01 00:00:00